MGH Study: Vitamin D Supplements Don’t Reduce Depression Risks

Vitamin D is most strongly associated with healthy bones. It promotes calcium absorption to strengthen bones and is needed for bone growth and bone remodeling. Vitamin D also plays key roles in cell growth, and neuromuscular and immune function.

But studies have also found that low levels of vitamin D (25-hydroxy vitamin D) were associated with a higher risk for depression later in life. To determine whether taking vitamin D supplements could help protect against depression, Massachusetts General Hospital psychiatrist Olivia I. Okereke, MD, led a study that included more than 18,000 men and women ages 50 and older.

“There was no significant benefit from the supplement for this purpose,” Dr. Okereke says. “It did not prevent depression or improve mood.”

Though vitamin D may not help you avoid depression, you may benefit from supplementation in other ways. Many people take vitamin D supplements for bone and metabolic health, though some studies have raised questions about just how much help vitamin D provides in lowering the risk of osteoporosis, for example. “It’s not time to throw out your vitamin D yet, though, at least not without your doctor’s advice,” Dr. Okereke says.

In addition to supplements, vitamin D is available in certain foods. Salmon, trout and several other types of fish are the best sources. Many milk, cereal, and orange juice products are fortified with vitamin D. And when exposed to sunlight, your skin manufactures its own vitamin D. Many people are advised to take vitamin D supplements if they have limited sun exposure or are at high risk for osteoporosis.

If you are concerned about your vitamin D levels, talk with your doctor. And if you are experiencing depressive symptoms, talk with your physician or a mental health professional.

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