Newsbriefs: Cancer Treatment; Cancer Fatigue

Potential New Treatment for Cancer Metastasis.

A new class of drugs targeting estrogen positive breast cancer, already approved by the U.S. Food and Drug Administration, may be effective also in treating triple-negative breast cancer, Mayo Clinic researchers announced. CDK4/6 inhibitors could prevent the spread of these cancers to distant organs, however, they do not affect the rate of cancer growth, researchers said. CDK4/6 governs a cancer metastasis protein, SNAIL. It’s possible the drugs could be used with other cancers that have a high level of SNAIL. (Nature Communications, Jan. 9, 2017.)

Cancer Fatigue Best Managed with Exercise, Behavioral Therapies.

Side effects of cancer treatments frequently include extreme fatigue, depression, anxiety, pain, and sleep disturbances. Researchers at the University of Rochester found that exercise and psychological intervention can help more in combating the fatigue, alone or in combination, rather than pharmaceutical interventions. Researchers found cognitive behavioral therapy was the most effective psychological intervention after primary treatment takes place. (JAMA Oncology, online March 2, 2017.)

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