Microbiome composition varies based on sampling time, mouse study finds

The microbiome has immense power to shape health outcomes. The bacteria that take up residence in the human body, including the gut, have been shown to impact health and disease, including neurodegenerative disorders. Medical research is invested in finding ways to reconstruct healthy microbiomes to help cure some of those ills. 

But like many fields in science, microbiome research is suffering from a reproducibility crisis. Eating, sleeping, and exercising can all affect the types and amounts of bacteria in the body, which can in turn make it difficult to replicate experimental outcomes. And in a new study, researchers highlight yet another confounding factor contributing to the problem: time.

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