Tom Nolan’s research reviews—18 May 2023

Out-of-office remindersChecking blood pressure using a 24 hour blood pressure monitor is referred to as out-of-office blood pressure in the US. According to a new study in the Lancet, it seems that, when it comes to diagnosis and monitoring of hypertension, we should keep the out-of-office on. The observational cohort study of a registry of over 50 000 patients in Spain compared blood pressure measured in a clinic with out-of-office blood pressure and each method’s association with all-cause and cardiovascular death over a median 9.7 year follow-up period. The 24 hour blood pressure measurements more closely correlated with all-cause mortality than clinic blood pressure—although a linked editorial asks whether some of the difference may reflect the quality of measurements performed in clinics.Lancet doi:10.1016/S0140-6736(23)00733-XOnce weekly insulin: onwards and upwardsOnce weekly basal insulin may soon become an option for people with type 2 diabetes, after an open label trial found that once…
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