STAT+: Mirati’s KRAS-blocking lung cancer drug clears safety hurdle in combination study
Mirati Therapeutics said Monday that its KRAS-targeting cancer drug called adagrasib combined with another immunotherapy was well-tolerated by patients with lung cancer — avoiding the serious liver side effects and treatment discontinuations that have stalled similar efforts by Amgen.
The new safety data are a boost to Mirati’s efforts to expand the number of patients with KRAS-mutated lung cancer who might benefit from adagrasib — and help the drug grow into a commercial blockbuster.
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