An mRNA vaccine boost may help CAR T-therapy treat solid cancers
NEW ORLEANS — While CAR T-therapy has cured some people with blood cancers, this form of immunotherapy has so far produced lackluster results for solid tumors like lung or kidney cancer. But a new early-phase clinical trial presented on Sunday at the American Association of Cancer Research (AACR) conference suggests that CAR T-cells may be able to shrink some solid tumors — as long as it gets a boost from an mRNA vaccine from BioNTech.
BioNTech became a household name thanks to the Covid-19 vaccine it developed with Pfizer. Before the pandemic emerged, the company was a relatively small biotech firm focused on developing mRNA vaccines for treating cancer. Today it’s valued at $42 billion, based on its stock price, and the new data show a preliminary look at how its technology might develop new cancer treatments.
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