STAT Plus: ‘Inactive’ drug ingredients are not always inactive, study finds

What’s in that pill you just swallowed?

The label on the bottle lists the drug’s active and inactive ingredients, but new research concludes some of those “inactive” ingredients aren’t so inactive. Whether these extra substances, in everything from ibuprofen to antihistamines to antacids, add color, preservatives, or fillers, some of them can also interact with a medication’s biological target. That could potentially cause side effects, though the study didn’t determine whether the ingredients in fact do so.

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