STAT Plus: The bearish view of Acadia Pharma’s antipsychotic drug takes a hit with positive trial results

Did the critics of Acadia Pharmaceuticals — and I’m very much included in that group — underestimate the efficacy of the drugmaker’s antipsychotic medicine Nuplazid? Or, did we fail to appreciate Acadia’s cleverness in designing a clinical trial for a mediocre medicine that could still deliver a positive result?

Maybe I’m stubborn, but I lean towards the latter. Still, there is no denying that Monday is a very good day for Acadia and those who believe in Nuplazid’s potential to be a more widely used antipsychotic drug. A Phase 3 clinical trial investigating Nuplazid as a treatment for dementia-related psychosis was stopped early for positive efficacy, Acadia announced.

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