A new ‘DNA microscope’ peers deep inside living cells

You could probably find a few biologists who are diehard protein partisans, and others who love lipids, but if a genie granted them one wish for what they could see inside living cells, most would pick DNA.

Joshua Weinstein of the Broad Institute of MIT and Harvard spent the last six years almost singlehandedly working to fulfill that wish, and on Thursday he unveiled the result: a “DNA microscope” that shows not only the locations of DNA (and its cousin, RNA) in a cell but also the precise nucleotide-by-nucleotide identity of each molecule.

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