In the hunt for novel antibiotics, will new technology overtake underwater exploration?
LAKE SUPERIOR — Choppy, windswept waves slap at the hull as our boat nears the…
Category: In the Lab
Never-smokers’ lung cancers are genetically different from smokers’ tumors, study shows
Researchers have identified unique genetic signatures of lung cancer in people who never smoked cigarettes,…
Scientists engineer nasal cartilage cells to repair aching knees
In osteoarthritis of the knee, cartilage that should cushion the bones erodes, leaving people in…
Does breast density matter for older women’s risk of cancer?
Breast density is a known risk factor for developing breast cancer, but that well-accepted research…
A lucky few seem ‘resistant’ to Covid-19. Scientists want to know why
Her husband collapsed just before reaching the top of the stairs in their small one-bedroom…
STAT+: A new technology, based on a quirk of evolutionary biology, may be the next big thing for CRISPR
On a chilly morning last November, Michael Segel stepped through the glass doors of the…
STAT+: Discovery of rare mutation in a brain protein adds fuel to debate over cause of Alzheimer’s disease
In 2014, two siblings came to see Lena Kilander about some of the problems they’d…
STAT+: New immunotherapy approach wiped out tumors in two patients with advanced lung cancer, study reports
Drugs called immune checkpoint inhibitors have transformed treatment of many types of tumors, but metastatic…
STAT+: Scientists plumbing mysterious RNAs in the human genome find a possible treatment for an inherited disorder
When hundreds of scientists from around the world finally pieced together a draft of the…
Large study finds genetic signals that might be used to predict early menopause
A large new study scanned the genes of hundreds of thousands of women near the…
In world’s first genetically engineered marsupials, scientists get a fresh window into human biology
When the pile of opossums arrived at John VandeBerg’s lab from the Smithsonian’s National Zoo…
By creating mouse eggs entirely from scratch, researchers raise the prospect of a futuristic fertility treatment
The tiny clump of mouse cells didn’t look like an ovary. For one thing, it…
Researchers use machine learning to translate brain signals from a paralyzed patient into text
Assistive technologies such as handheld tablets and eye-tracking devices are increasingly helping give voice to…
Landmark gene therapy trial points to a wider window to alter course of rare disease
The suspicion that something was wrong started when the 1-year-old girl’s parents noticed she had…
Gene hunters turn up new clues to help explain why Covid-19 hits some people so hard
On March 16, 2020, five days after the World Health Organization declared Covid-19 a global…
Scientists devise a battery-free pacemaker that can be absorbed by the body
Scientists have designed a temporary, battery-free pacemaker that can be broken down by the patient’s…
Researchers raise concerns about using genetic risk scores to pick ‘healthier’ embryos
As more people turn to in vitro fertilization for help with conceiving, a host of…
Could editing the genomes of bats prevent future coronavirus pandemics? Two scientists think it’s worth a try
Amid the devastating Covid-19 pandemic, two researchers are proposing a drastic way to stop future…
STAT+: Gene therapy to regenerate cardiac muscle after a heart attack passes a key test in pigs
By delivering a viral payload of gene silencers directly to the heart, scientists have developed…
After racing to help the world understand Covid-19, scientists grapple with how to pick up the research they put on hold
In the earliest days of the pandemic, it was the small, long-underfunded coterie of dedicated…
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How the pandemic has reshaped collaboration — and competition — in science
For as long as people have pointed telescopes at the night sky and slipped drops…
Gender bias toward men in patent awards results in less biomedical innovation for women, study suggests
Research has long shown that fewer patents are awarded to women than to men. Now…
STAT+: Scientists unshelve a decades-old antibiotic to fight a new foe — ovarian cancer
Ovarian cancer, which kills about 15,000 Americans every year, has historically been one of the…
STAT+: Scientists CRISPR patients’ own immune cells in bid to shrink hard-to-treat GI tumors
Last year, researchers at the University of Pennsylvania, led by immunotherapy pioneer Carl June, showed…
A safer, low dose of laughing gas may be enough to help some patients with major depression, study finds
Laughing gas may be most associated with its use in dentistry, but in recent years,…
With a souped up synthetic genome, scientists make bacteria impervious to viral attack
Two years ago, scientists in Britain swapped out the DNA of the bacteria Escerichia coli…
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Researchers claim they have sequenced the entirety of the human genome — including the missing parts
An international team of scientists says it has sequenced the entirety of the human genome,…
STAT+: From two unusual organ donations, scientists garner a unique trove of single-cell genetic data
Late at night, in a California hospital, a brain-dead patient was being prepared to offer…
Scientific panel loosens ’14-day rule’ limiting how long human embryos can be grown in the lab
An influential scientific panel cracked open the door on Wednesday to growing human embryos in…
With engineered proteins, scientists use optogenetics for the first time to help a blind patient see again
Somewhere in Paris, in a white room, seated at a white table, a man wearing…
In new study, stem cells self-organize into a mini model of a beating heart
Researchers have worked for years to create organoids — miniature cellular structures that recapitulate features…
AIDS virus used in gene therapy to fix ‘bubble baby’ disease
A gene therapy that makes use of an unlikely helper, the AIDS virus, gave a…
Reawakened immune cells show promise in mice against zombie cells tied to diseases of aging
Scientists have started to test whether natural killer, or NK, cells can be trained to…
HHS to prioritize newborn screening programs’ pipette tip orders
Programs that screen newborns for potentially deadline genetic conditions will now have higher priority when…
STAT+: Glowing tumor-munching cells, captured on video, show the promise of a new approach to CAR-T cancer therapy
Wendell Lim stared at the video playing on his computer screen in amazement. In the…
How blackouts, fires, and a pandemic are driving shortages of pipette tips — and hobbling science
The humble pipette tip is tiny, cheap, and utterly essential to science. It powers research…
Covid-19 gave scientists an opening to better understand how brain disorders arise
While the Covid-19 pandemic put many human research studies on hold, neuroscientist Grainne McAlonan of…
In mouse experiments, scientists unlock the key to scar-free skin healing
Scars. Like memories, we all have them. When you look at a scar you might…
STAT+: Beam Therapeutics unveils new CRISPR base editing tool to target the sickle cell mutation
Right now, trillions of donut-shaped red blood cells are whizzing through your arteries, ferrying oxygen…
International team creates first chimeric human-monkey embryos
A team of scientists from the U.S., China, and Spain reported Thursday they have created…
An HIV lab’s pivot to develop a single-dose Covid-19 vaccine wins STAT Madness ‘Editors’ Pick’
On Jan. 10 last year, Dan Barouch and members of his vaccine research lab were…
Researchers pursuing novel treatments for herpes infections and diabetes win STAT Madness
From curing herpes to treating diabetes in a new way, their innovations might one day…
Watch: Microrobots fight brain tumors in mice
Scientists have created a microrobot that can pass the near-impenetrable blood-brain barrier to treat brain…
STAT+: New monkey model of Alzheimer’s disease may accelerate search for human treatments
Researchers reported Thursday that they have created a new model for studying treatments of Alzheimer’s…
New models could help scientists study the earliest stages of embryonic development
A pair of research teams unveiled two new ways to replicate a key structure from…
STAT+: ‘We’re only going to cure diseases if we understand them’: Whitehead director advocates for basic science
Ruth Lehmann became director of the Whitehead Institute for Biomedical Research in July 2020. That…
STAT+: ‘It looks like a spaghetti bowl’: Scientists reveal a precise structure in a fabled worm’s tangled brain
Using Facebook-like algorithms, a bespoke microscope, and hefty doses of patience, a team of scientists…
The new leader of 500 Women Scientists on finding community and supporting women of color in STEMM
In the spring of 2019, Lauren Edwards was a graduate student studying neuroscience at Emory…
STAT+: STAT+ Conversations: A conversation on race, science, and advocacy with Black in Neuro founder Angeline Dukes
Editor’s Note: A livestream of the conversation will be embedded below at 12 p.m. ET….
Studying Neanderthal mini-brains, scientists unlock clues to modern human evolution
Hoping to learn what sets our brains apart from those of the Neanderthals, scientists have…