Four neuroscientists win Kavli Prize for discovering genes behind serious brain disorders
Four neuroscientists who discovered the genes involved in a host of serious brain disorders won…
Category: In the Lab
Child’s autopsy from 2008 becomes a clue to mystifying polio-like illness
Within days, the boy went from having cold symptoms to being unable to walk. To…
STAT+: New kind of off-the-shelf cancer vaccine reduces metastasis in animal experiments
About 15 years ago, cancer researchers noticed a trend. Some of the patients they were…
As reports of ‘Paxlovid rebound’ increase, Covid researchers scramble for answers
As he was treating some of the nation’s first coronavirus patients, Andre Kalil noticed something…
Buffalo shooting ignites a debate over the role of genetics researchers in white supremacist ideology
The 18-year-old gunman suspected of carrying out a racist attack that killed 10 and injured…
Cancer experts hail a molecular ‘black box’ that records how cells fly into tumor territory
Biologists Tyler Jacks and Jonathan Weissman’s mice may look like any other lab mice —…
Publication of the ‘Google Maps’ of human cells is a milestone. A pioneer of the project explains why
Just under your skin lie whole aqueous worlds, where trillions of cells spark and beat…
In radical claim, study suggests inflammation wards off chronic pain instead of causing it
For two decades, Luda Diatchenko investigated the underlying biology of pain like a detective chasing…
Transfusion of brain fluid from young mice is a memory-elevating elixir for old animals
For a human, one of the first signs someone is getting old is the inability…
A new ‘master regulator’ could call the tune for hair cells essential to hearing
The act of hearing is like a ballroom dance, scientist Jaime García-Añoveros says. Tiny hair…
The brain ‘learns’ to have seizures more efficiently and frequently over time, mouse study shows
Calculus. Ballroom dancing. The words to your favorite song. There’s practically no limit to what…
Hundreds of families share a lethal inheritance. This kidney researcher hopes to break the chain
Autumn Steen roiled in the pew of the chapel, Bowditch Union Free Will Baptist Church…
STAT+: Multiple myeloma is usually detected late. Some researchers think a precursor could help catch it early
For all the recent advances in treating multiple myeloma, scientists have only inched forward in…
STAT+: Lighting up cancer cells with pH-activated nanoparticles
On a screen at the American Association of Cancer Research (AACR) conference on Saturday, one…
STAT+: When a dire text message interrupted his talk, this doctor’s cancer research became painfully real
SAN DIEGO — If you’d seen him, you wouldn’t have known Scott Lippman was living…
Research on mice that ‘sweat out’ fat wins STAT Madness for University of Pennsylvania
Pizza rat, watch out: pizza-faced mice are on their way to stealing your crown. A…
.jpg)
Obesity can turn a helpful immunotherapy into a harmful one, mouse study shows
Researchers have long known that obesity rewires the immune system. Now a new study suggests…
.jpg)
STAT+: Scientists test tetanus bacteria as a weapon to target pancreatic tumors
Pancreatic cancer has proved one of the most deadly forms of the disease, and the…
With new ‘brain-reading’ research, a once-tarnished scientist seeks redemption
Niels Birbaumer, once a prominent neuroscientist at the University of Tübingen in Germany, fell hard…
Swapping out the brain’s cleanup crew treats neurological disease in mice, study shows
From anemia to leukemia, unhealthy cells can make for unhealthy people, but replacing these cells…
Newly discovered brain cells may be a memory filing system, study suggests
A scientist opens a laptop in front of a patient. On screen, a boy, tied…
Organoids reveal the tipping point when kidney damage turns irreversible
Chronic kidney disease is a serious medical problem that changes the lives of about 13%…
Provocative new findings suggest a surprising cause of Down syndrome: cells linked to aging
Down syndrome is the most common genetic disorder, impacting about 1 in 700 newborns around…
STAT+: 3 CRISPR editing innovations to watch in 2022
During the first year of the Covid-19 pandemic, many of the world’s scientists — including…
To lawyers, conviction of Harvard chemist with China ties shouldn’t chill science. Researchers aren’t so sure
The trial was supposed to be a bellwether — an indicator of whether federal investigators…
For an antiviral researcher, Covid brings a flood of attention — and opportunity
In February 2020, Jeffrey Glenn was prepping for a meeting at the Food and Drug…
Scientists are just starting to tease out the microbiome’s role in CAR-T outcomes among cancer patients
As cancer-killing CAR-T cells course through the body, they make occasional pit stops at the…
STAT+: Mutations tied to blood cancers and other diseases may surprisingly protect against Alzheimer’s
ATLANTA — When key mutations strike bone marrow stem cells, known as hematopoietic stem cells,…
STAT+: In the blood of marathoning mice, scientists find clues to how exercise benefits the brain
If you give a mouse a wheel, it will run, and run, and run: between…
Is cancer biology research reproducible? After a decade of work, the answer still isn’t clear
Replication is something of a litmus test for scientific truth, and cancer biologists at the…
We’ll know more soon about Omicron. Here’s how to interpret the coming flood of data
At some point in the next few weeks, scientists will start releasing data from lab…
Most advanced lab-grown human embryos prompt a pressing question: Are they getting too real?
The stem cells were no more than a week old when scientists moved them from…
STAT+: Liquid biopsies could help screen for countless cancers. But who should get them?
By the time cancer is discovered, it’s often too late to change its course. Close…
Lessons from a Flint water crisis researcher about building trust in science during the pandemic
Siddhartha Roy was only a graduate student in 2015 when he found himself in the…
Nancy Hopkins, pioneering biologist and advocate for gender equity in science, wins STAT Biomedical Innovation Award
Nancy Hopkins, an MIT professor who has made significant strides in molecular biology and a…
Scientists report finding a second person to be ‘naturally’ cured of HIV, raising hopes for future treatments
One evening in March 2020, a doctor walked out of a hospital in the Argentine…
Using optogenetics, scientists pinpoint the location and timing of memory formation in mice
A mouse finds itself in a box it’s seen before; inside, its white walls are…
5 years of progress: The first STAT Wunderkinds on their biggest challenges and proudest moments in science
Next week, STAT will unveil its fifth class of Wunderkinds, a group of doctors and…
STAT+: Scientists find a clue to why some people have ‘Alzheimer’s brains’ but no dementia
Defective proteins clump into toxic plaques and tangles. Plaques of amyloid and tau tangles kill…
The vast majority of genes have been tied to cancer — and that can complicate research
João Pedro de Magalhães scours the human genome for clues that might help us understand…
STAT+: In research on mice, scientists use light to paint to a more precise target for CAR-T to attack tumors
In a dark lab, a sedated mouse laid face down on the counter, its backside…
Philanthropist-funded study at a prestigious hospital raises thorny questions about clinical research
The opportunity seemed too good to pass up. It was 2020, and the CEO of…
STAT+: New CRISPR tools could fix diseases caused by large DNA rearrangements, scientists report
Ever since the now Nobel-winning discovery of CRISPR genome editing in 2020, scientists have been…
HHMI philanthropy devotes $2 billion to boost inclusion and equity in biomedical sciences
Saying bold steps are needed to improve racial, ethnic, and gender diversity in science, the…
Mouse experiments with a decades-old drug suggest a new approach to Alzheimer’s treatment
A generic drug used widely to treat swelling associated with hypertension and heart failure showed…
Two scientists win chemistry Nobel for discovering a new way to construct molecules, speeding up drug development
Scientists Benjamin List and David MacMillan won the Nobel Prize in chemistry Wednesday for discovering…
In research first, jolts from a customized brain implant provided immediate relief to a severely depressed patient, scientists say
When Sarah, 36 years old and severely depressed, sat down in a lab with a…
STAT+: Genetic information can be messy. Mapping proteins could offer a clearer view of what’s driving cancer
Scientists have unveiled new maps of the protein networks underlying different types of cancer, offering…
New study revives a Mozart sonata as a potential epilepsy therapy
Could this be the return of the “Mozart effect”? In 1993, researchers reported that after…
Return of the mammoth? George Church-backed company launches with $15 million for elephant-sized quest
Harvard scientist George Church, a pioneer of both DNA sequencing and gene editing, has been…