LYNPARZA® (olaparib) Phase 3 PROfound Trial in HRR Mutation-Selected Metastatic Castration-Resistant Prostate Cancer Met Primary Endpoint
AstraZeneca and Merck’s LYNPARZAImproved Radiographic Progression Free Survival vs. Standard of Care in Patients Selected for BRCA 1/2 or ATM Mutations
Only PARP Inhibitor with Positive Phase 3 Results in Four Different Cancer Types
KENILWORTH, N.J.–(BUSINESS WIRE)–AstraZeneca and Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced positive results from the Phase 3 PROfound trial of LYNPARZA in men with metastatic castration-resistant prostate cancer (mCRPC) who have an homologous recombination repair gene mutation (HRRm) and have progressed on prior treatment with new hormonal anticancer treatments (e.g. enzalutamide and abiraterone).
Media Contacts:
Pamela Eisele
(267) 305-3558
Steve Wanczyk
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Investor Contacts:
Teri Loxam
(908) 740-1986
Michael DeCarbo
(908) 740-1807

