Depression: How brain scans helped predict long-term treatment outcomes

Depression has many faces. Some people can’t sleep, while others struggle to get out of bed. Even though symptoms and severity can vary from person to person, a recent study found that a specific brain circuit might be associated with the mental malady. 

Located in the prefrontal cortex, the brain’s cognitive control circuit plays a part in our attention, goal-setting behavior and other executive functioning. Depression often impairs these functions, and psychiatrists have developed non-pharmacological therapies such as cognitive behavioral therapy to address these problems. Capturing this circuit’s activity might eventually help psychiatrists predict the course of someone’s depression.

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