Mental health benefits of gender-affirming hormones for teens persist for two years in new study

Trans and nonbinary teenagers who receive gender-affirming hormones experience less depression and anxiety and more satisfaction with life than before the treatment, according to a new study published Wednesday in the New England Journal of Medicine.

Researchers followed over 300 adolescents across the U.S. for two years after initiating hormone treatment. The results augment a substantial body of research that shows gender-affirming care improves mental health, but most previous studies had been done with smaller, single-location cohorts and shorter follow-up windows. The new paper also focuses primarily on hormone therapy, while earlier work often included a variety of care options, including drugs to delay onset of puberty.

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