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Listen: Your guide to Wegovy’s blockbuster heart study
Is Wegovy the future of cardiology? Can Novo Nordisk ever make enough of it? And…
Category: The Readout LOUD
Listen: Biotech layoffs, eye drug drama, & gene therapy milestones
Can biotech startups survive a downturn? Is Covid-19 a good business? And when did ophthalmology…
Biogen’s sticky situation, Wegovy’s risks, & biotech insider trading
Why do CEOs talk like that? Do biotech stock tips make good gifts? And what…
BridgeBio’s big week, Lilly’s Alzheimer’s data, & succession at Stanford
What can Homer teach us about biotech? Has Big Science gotten too big? And what’s…
Listen: Wegovy in the brain, pivotal Alzheimer’s data, & pulling Threads
Is Wegovy really a brain drug? Which Alzheimer’s disease treatment works best? And what’s the…
Listen: Novavax’s CEO promises a turnaround & how Lilly roiled the obesity market
Can Novavax finally get it right? What’s a “triple-G” drug? And is Novo Nordisk losing…
Listen: Messy PBM conflicts, debatable vaccines, & the future of flu season
Who’s watching the drug price watchmen? Are RSV vaccines too expensive? And is it finally…
Listen: Biogen’s messy board, Laronde’s data problem, & the downside of a boom
Can unicorns survive without data? Did biotech get over its skis? And what is going…
Listen: Merck v. USA, the best of ASCO, and Leqembi at the FDA
Are drug prices protected by the Constitution? Will Medicare embrace Alzheimer’s disease treatments? And should…
Listen: Fake medical devices, real cancer drugs, & curious Ozempic effects
Why are fake medical devices more lucrative than real ones? Is Ozempic a neurological treatment?…
Listen: ChatGPT in medicine, a boom in weight loss pills, & Sarepta at the FDA
Can AI diagnose a disease? Are Wegovy’s days numbered? And what makes AI hallucinate? We…
Listen: The FTC v. Amgen, Sarepta’s future, & Galapagos’ turnaround
Does the FTC have it out for pharma? What does it take to make an…
Listen: Pharma vs. PBMs, Sarepta at the FDA, & a bold idea gone awry
Is there a Bermuda Triangle of drug prices? Do FDA advisers matter? And when should…
Listen: Lilly’s Alzheimer’s success, a milestone FDA approval, & Moderna’s shrinking business
What’s the future of Alzheimer’s disease treatment? How do you pivot from a pandemic? And…
Listen: Explaining the E.U.’s pharma overhaul, Lilly’s booming business, & a long-awaited drug approval
Is a specter haunting Europe? Will Eli Lilly usurp Johnson & Johnson? And what does…
Listen: Sarepta’s pivotal moment, biotech’s big week, & the future of Covid boosters
How can you be sure a gene therapy is working? What does $11 billion get…
Listen: How the legal battle over abortion could thwart research, plus: the FDA ‘bully pulpit’ and Moderna’s future
Is pharma facing an existential threat? How do you get CEOs to speak out? And…
Listen: Illumina’s boardroom intrigue, the next big Alzheimer’s readout, & J&J’s creative lawyers
Is Illumina the Disney of biotech? Does the Texas two-step work after all? And can…
Listen: Biotech’s monkey shortage, the broken generics market, & conference cancel culture
What happened to the market for monkeys? Are some drugs too cheap? And why are…
Listen: Bancel v. Bernie, Sarepta’s FDA runaround, & Regeneron’s ever-growing blockbuster
What would Jonas Salk say if he were here right now? How do you know…
Listen: SVB’s long biotech shadow, pushy AI algorithms, & Icahn v. Illumina
Is AI dictating patient care? What happens when your bank falls apart? And can Illumina…
Listen: Robert Califf on how drugs get approved, plus the nascent revolution in obesity
What keeps the FDA commissioner up at night? How will Ozempic change the world? And…
Listen: Pharma blockbusters, pandemic policy, & legal chicanery
Is the next Lipitor on the way? When is a pandemic over-over? And what’s a…
Listen: George Scangos’ retirement, annual Covid vaccines, an Alzheimer’s drug rejection
Who needs an annual Covid jab? Why did the FDA reject an Alzheimer’s treatment? And…
Listen: How blockbusters get made, new vaccines for RSV, and mRNA’s Q score
Where do new drugs come from? Does science need billionaires? And do normal people care…
#JPM23 in review, the year ahead, & the merits of Miami
What happened at biotech’s big reunion? Will this year be better than the last? And…
Listen: #JPM23, the future of Alzheimer’s, & rising Covid variants
What does 2023 have in store for biotech? How can the FDA win back trust?…
2022 in review, CEO indictments, & the year ahead
When does optimism become criminal? Why can’t biotech find its way back? And what’s going…
Listen: Leaky health data, ASH22, & what it takes to get booed by your peers
Why do billionaires get booed? How does Facebook end up with sensitive health data? And…
The ‘electric vehicles’ of pharma, Illumina’s boondoggle, & a Theranos sentencing
Who gets dibs on in-demand medicines? Can you get a refund on an $8 billion…
Listen: Wither PhRMA, Alzheimer’s treatment data revealed, and the first fecal microbiome drug approval
A big Alzheimer’s treatment data reveal. The first FDA-approved fecal microbiome drug. And a stinging…
Listen: Roche’s failure, Eisai’s success, and a live AMA
How do Alzheimer’s drugs even work? Can biotech people bake? And do we even like…
Listen: Biogen’s new CEO, how the midterms affect science, & a biotech bankruptcy
How can Biogen right the ship? What happened to that “red wave”? And what can…
Listen: How the biotech revolution could come apart at the seams
What’s the atom bomb of biology? Why don’t we run better clinical trials? And how…
Listen: Anti-science at the polls, a biotech odd couple, & the stakes of the midterms
Can Covid denialism get you elected? How is the music business like biotech investing? And…
BU’s Covid tinkering, FDA on trial, & why it’s hard to take drugs off the market
What happens when approved drugs turn out not to work? Is it OK to make…
BIO’s messy transition, mRNA’s future, & Biogen’s next CEO
What’s going on at biotech’s lobbying organization? Where does mRNA go from here? And what…
Listen: Nobels for science, biotech dealmaking, & a friendly FTC
What can we learn from mummy DNA? Is Pfizer single-handedly propping up biotech? And how…
Listen: A surprise success in Alzheimer’s and how FDA history seeded modern controversy
Does the latest Alzheimer’s disease drug actually work? When does the FDA call in security?…
Listen: Biden’s Covid declaration, twilight of the SPAC, & genome editing 2.0
When is a pandemic “over?” Did biotech over-SPAC? And what can’t be CRISPR’d? We cover…
Listen: Pharma’s telehealth gold mine, the return of the biotech IPO, & a merger deferred
Is online prescribing a good idea? When is $2 billion not a lot of money?…
Illumina’s $8 billion limbo, a new treatment for ALS, & Emirati biotech funding
Is Illumina a victim of its own success? What makes the FDA change its mind?…
Listen: The anti-aging research boom, the Godfather of biotech, & the future of Biogen
What can worms teach us about immortality? How does one become the Godfather? And where…
Fauci’s non-retirement, grading biotech VCs, & a bellwether IPO
Are we getting Covid-19 boosters wrong? Which venture capitalists are missing their marks? And what’s…
Listen: Private equity in autism care, a watershed FDA approval, and the future of ALS treatment
How did autism care become a big business? Can gene therapy be profitable? And whatever…
Listen: Big egos in Big Science, the return of Merger Monday, & the fallout over drug pricing
Are biotech’s fortunes finally changing? Is Big Science impeding actual science? And what will Medicare…
Listen: The last-minute push for drug pricing reform, Alnylam’s success, and Sarepta’s gamble
Is drug pricing reform really happening this time? Are things finally turning around for biotech?…
Listen: Helen Branswell on monkeypox, plus: an FDA controversy and fake Alzheimer’s data
Can monkeypox be contained? Are snortable Covid-19 vaccines on the way? And when is a…
Listen: Well-paid CEOs, behind the scenes at Moderna, & Biogen’s CEO search
Does any CEO deserve $500 million a year? How did Moderna hit it big? And…
Listen: CRISPR for the heart, biotech’s recovery, & what it means to be a ‘hot girl’
Can CRISPR edit out a heart attack? What happens on #GutTok? And is health care…