Animal studies lend support to an innovative HIV vaccine strategy — but there’s still a long way to go
HIV has long stumped immunologists looking to develop an effective vaccine. All of the most…
Category: In the Lab
STAT+: ChatGPT for genomes: introducing a CRISPR-designing generative AI
In 2018, during her chemistry Nobel Prize lecture, Frances Arnold noted that scientists had arrived…
STAT+: Data integrity watchdogs call for stronger safeguards in scientific journals
SAN FRANCISCO — According to Elisabeth Bik, a scientific watchdog who has discovered thousands of…
To detect risk of stroke, tiny probe acts ‘like a microscope’ inside brain’s blood vessels
To better understand problems in the brain’s blood vessels that may lead to stroke, we…
STAT+: Harvard scientists unveil the most detailed map of the brain ever: ‘It’s an alien world inside your own head’
About 10 years ago, a small piece of human brain arrived in the lab of…
Q&A with Jennifer Adair, researcher on a mission to increase global access to gene therapies
BALTIMORE — Gene and cell therapies have transformed a handful of devastating disorders in the…
Cell therapy fails to slow early type 1 diabetes, but safety is established
Tolerance is the holy grail in calming autoimmune disease, a truce in the immune system’s…
Meet the scientist sending tumors into space
What happens when you catapult cancer into space? Or shoot stem cells toward the stars?…
Scientists spot an orangutan using a plant to treat his own wound in the wild
When male Sumatran orangutans let out a long call, they’re usually trying to grab female…
STAT+: Biological clocks could be the key to longer, healthier lives. But scientists don’t yet agree on what ‘aging’ is
It’s no secret that a lucky few seem to glide into old age, the years…
STAT+: Experimental gene therapy seems to alleviate skeletal defects tied to rare inherited disease, study shows
LONDON — In 2021, a team of Italian researchers reported that an experimental gene therapy…
STAT+: To regrow blood vessels after heart attack, a little transplant of mitochondria goes a long way in mice
Blood vessels in the legs or heart sustain considerable damage when they are narrowed by…
Exercise is good for health — but why? A study in rats offers insight
It’s widely known that exercise is beneficial for health. Yet science doesn’t have a clear…
STAT+: Brain biopsies on ‘vulnerable’ patients at Mount Sinai set off alarm bells at FDA, documents show
NEW YORK — By the time Peter Bauman considered deep brain stimulation, he was desperate….
STAT+: Former MIT biologist David Sabatini, forced out after sexual harassment accusations, to lead new Boston team
Former MIT and Whitehead Institute star biologist David Sabatini, who lost his lofty positions after…
STAT+: After AI protein folding, David Baker’s lab identifies millions of smaller drug candidates
University of Washington professor David Baker has made a name for himself by borrowing computer…
STAT+: NIH postdocs will get a raise next year — but not as much as they hoped
The National Institutes of Health will raise the minimum salary for postdoctoral researchers to $61,008…
STAT+: In a scientific first, researchers use CRISPR base editing to treat liver disease in fetal monkeys
The ambitious idea of using CRISPR to cure genetic diseases before birth is one step…
STAT+: Dana-Farber retracts string of studies in systematic review of data integrity
An ongoing investigation into data integrity at Dana-Farber Cancer Institute has resulted in a string…
What the noses of mice can tell us about the inheritance of trauma
In the final year of World War II, Nazi troops starved the Netherlands in a…
STAT+: When a cancer drug fails, oncologists often fly blind. A precision technique might light the way
It seemed as if Logan Jenner had the best possible chance for a cure. Diagnosed…
STAT+: New liquid biopsy screening test for pancreatic cancer shows promise in early data
For the vast majority of pancreatic cancer cases, the tumor grows undetected until it has…
STAT+: Cancer is rising among the young. Study suggests it’s because their cells are aging faster
SAN DIEGO — Cancer cases among younger people have been rising for years, a trend…
What ‘de-extinction’ of woolly mammoths can teach us: a Q&A with evolutionary biologist Beth Shapiro
Humans have long tinkered with the evolutionary trajectories of other species. Thousands of years ago…
STAT+: Scientists uncover potential path to treating deadly childhood tumor
Most targeted cancer drugs work like tranquilizer darts, snaring an overzealous gene that has spurred…
Why researchers think human milk could repair the gut microbiome and reduce infections
For babies who are breastfed, their first source of sustenance is filled with proteins, sugars,…
Gut bacteria could play role in kidney autoimmune disease, study shows
Right now, inside your digestive tract, there are trillions of bacteria, fungi, and viruses that…
STAT+: Borrowing an idea from cancer immunotherapy, scientists make old-mice immune systems youthful again
One of the indignities of getting older is the way your body’s defenses against microbes…
Pregnancy increases biological age — but recovery and breastfeeding can undo the damage, study finds
Pregnancy is a known stressor on the body. But a new study published on Friday…
Male birth control research wins audience over at STAT Madness event
What happens when too many excellent, pioneering researchers enter a room? A little madness. That’s…
STAT+: U.K. health officials and researchers try to carve a path for more individualized genetic treatments
LONDON — Widespread genetic testing as well as the development of cutting-edge, customized genetic therapies…
Fetal tissue research gains in importance as roadblocks multiply
Scientists at the University of Wisconsin-Madison have spent years trying to unravel the details of…
STAT+: A scientific mystery highlights the blind spots in genomics databases
The two patients had both died young from heart problems. When researchers looked at their…
STAT+: In small study, baby aspirin cuts fat buildup in liver disease patients
Low-dose aspirin led to a reduction in liver fat among patients with metabolic-associated liver disease,…
Q&A: Is it time for scientists to rethink how they study sex in research?
Our understanding of sex has come a long way. Aristotle theorized that heat during conception…
What the brains of song birds can teach us about human stuttering
A symphony of synapses fires every time a songbird sings. For Erich Jarvis, a neurobiologist…
STAT+: Small studies offer hope CAR-T can fight an aggressive brain cancer
A series of new studies are raising hopes that CAR-T, a process in which treatments…
STAT+: Researchers create talking throat patch for people with voice disorders
Researchers at the University of California, Los Angeles have built a soft, adhesive patch capable…
STAT+: IVF doctors demand full details on fluid that grows embryos amid CooperSurgical lawsuits
Patients from all over the country are filing lawsuits against medical supply giant CooperSurgical, alleging…
Microplastics found in blood vessels linked to greater risk of heart problems, study finds
Micro and nanoplastics, tiny pieces of plastic scattered throughout the environment, have been increasingly found…
Air quality improvements belie rising racial and ethnic disparities in pollutant-related deaths, study finds
The U.S. is making progress in reducing the public health consequences of air pollutants and…
STAT+: Harvard longevity scientist sparks furor with claim about reversing aging in dogs
Renowned Harvard University geneticist and longevity researcher David Sinclair recently made an astonishing assertion: Scientists…
It’s time to stop treating menopause like a disease, researchers argue in series of Lancet articles
One in eight people is postmenopausal, and about 50 million women enter menopause every year….
Covid-19 increases risk of developing autoimmune disease, but vaccination helps, large study shows
Having Covid-19 increases a person’s risk of developing an autoimmune disease in the year after…
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In a first, fetal cell organoids generated from amniotic fluid, new study reports
As a fetus develops, its body is bathed in amniotic fluid: a warm, salty soup…
Q&A: Stem cell biologist predicts human embryo models could pave the way to organ transplants
A lot happens in the first month of human embryo development as a single cell…
Why do some women experience UTI pain with no clear infection? A mouse study offers clues
Each year, more than 400 million urinary tract infections occur in people around the globe….
‘Brain fog’ is one of Covid-19’s most daunting symptoms. A new study measures its impact
Of all the lingering symptoms of long Covid, difficulty focusing and thinking, known as brain…
Q&A: The scientific integrity sleuth taking on the widespread problem of research misconduct
Elisabeth Bik, a microbiologist by training, has become one of the world’s most influential science…
STAT+: MD Anderson tried — and failed — to resolve research credit dispute between two scientists, new documents show
Early last year, MD Anderson Cancer Center leadership had a problem on their hands: a…