Should patients requiring radiotherapy for breast cancer be treated with proton beam therapy?
What you need to knowProton beam therapy is a type of radiation therapy that uses…
Category: Uncertainties page
Are hard collars necessary for older people with odontoid neck fractures?
What you need to knowPatient age, frailty, comorbidities, and injury severity are important predictors of…
Is immobilisation required for toddler’s fracture of the tibia?
What you need to knowThere are no data or guidelines to suggest whether immobilisation is…
How should aerosol generating procedures be defined?
What you need to knowOpportunistic airborne transmission of aerosols can occur during activities and procedures…
Which treatments are safe and effective to reduce intracranial pressure following severe traumatic brain injury?
What you need to knowA tiered approach using multiple interventions to reduce raised intracranial pressure…
Is stem cell transplantation safe and effective in multiple sclerosis?
What you need to knowAutologous haematopoietic stem cell transplantation (aHSCT) is a relatively new treatment…
Who should consume high-dose folic acid supplements before and during early pregnancy for the prevention of neural tube defects?
What you need to knowGuidelines recommend 0.4 mg of folic acid per day in the…
What is the role of minimally invasive surgical treatments for benign prostatic enlargement?
What you need to knowNew minimally invasive surgical treatments for benign prostatic enlargement that do…
Is cerclage safe and effective in preventing preterm birth in women presenting early in pregnancy with cervical dilatation?
What you need to knowEmergency cervical cerclage is a potential treatment for women presenting with…
Should prehospital early warning scores be used to identify which patients need urgent treatment for sepsis?
What you need to knowMany prehospital early warning scores have been developed, based on a…
Should women with Lynch syndrome be offered gynaecological cancer surveillance?
What you need to knowLynch syndrome is an inherited genetic condition associated with an increased…
Does depression screening in primary care improve mental health outcomes?
What you need to knowInternational guidelines and practice differ regarding screening for depression; it is…
Which is the best model to assess risk for venous thromboembolism in hospitalised patients?
What you need to knowVenous thromboembolism in hospitalised patients can be potentially prevented through patient…
Should all pregnant women be offered testing for group B streptococcus?
What you need to knowMany countries have guidelines that recommend universal testing for group B…
Does self-management of vaginal pessaries improve care for women with pelvic organ prolapse?
What you need to knowSelf-management of vaginal pessary for pelvic organ prolapse may enable patient…
What level of immobilisation is necessary for treatment of torus (buckle) fractures of the distal radius in children?
What you need to knowEvidence suggests that most children with torus fractures of the distal…
Do PROMS improve outcomes in patients with depression in primary care?
What you need to knowPatient reported outcome measures (PROMS) are questionnaires used in the initial…
Is surveillance colonoscopy necessary for all patients with bowel polyps?
What you need to knowSurveillance colonoscopy is advised in some patients who have had bowel…
Is streaming patients in emergency departments to primary care services effective and safe?
What you need to knowCo-located primary care services have been introduced in emergency departments in…
What diagnostic strategies can help differentiate cellulitis from other causes of red legs in primary care?
What you need to knowRed legs owing to non-infectious causes are often misdiagnosed as cellulitis,…
What is the best method for managing early miscarriage?
What you need to knowGuidelines from the National Institute for Health and Care Excellence recommend…
Is there a place for intra-articular corticosteroid injections in the treatment of knee osteoarthritis?
What you need to knowIntra-articular corticosteroid injections possibly improve pain and function in the short…