Ann Robinson’s research reviews—4 August 2022

Nothing new under the sunThis US study of 200 people with poorly controlled type 2 diabetes (HbA1c>8.5% for over a year despite care in a diabetes clinic) found that a comprehensive telehealth intervention—including remote monitoring and support with diet, exercise, self management, medication, and mental health—improved HbA1c results at 12 months to a greater extent than a simpler intervention that only provided telemonitoring and care coordination (1.59% v 0.98%). Interestingly, the comprehensive intervention, which cost an extra $1519/patient/year to deliver, didn’t improve weight loss or depression, although it did improve self-rated diabetes-related distress and self-care. So, a greater level of support by a trained healthcare professional resulted in better outcomes—no surprise there.JAMA Intern Med doi:10.1001/jamainternmed.2022.2947High versus low dose tranexamic acidTranexamic acid (TA) is simple, cheap, and works a treat. It is known to reduce blood loss and transfusions in cardiac surgery. In this trial of 3031 patients in China who…
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