What do we know about covid-19’s effects on the gut?
What gastrointestinal symptoms can covid-19 cause?Lack of appetite, nausea, vomiting, diarrhoea, and abdominal pain. These may not be the symptoms people expect with covid, but around 50% of people experience them after SARS-CoV-2 infection, and in some people they’re the only symptoms.1 Gastrointestinal (GI) symptoms may be the first sign of infection or may develop later and persist as part of long covid.Sheena Cruickshank, immunologist at the University of Manchester, tells The BMJ why doctors didn’t initially recognise GI symptoms as part of covid-19. “The frequency of gastric symptoms—anorexia, pain, diarrhoea, vomiting, rectal bleeding—has varied considerably from 12-61% in publications,” she says, explaining that this variance may be due to GI symptoms not being reported as linked to covid. “However, it’s clear that this has the potential to be a major symptom.”When SARS-CoV-2, the virus that causes covid, enters the lungs it gains entry to epithelial cells by binding to…
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