Haytox: what is the evidence for a Botox spray for hay fever?

A spray treatment has gained popularity among people with hay fever in Australia and the UK over the past two years.1 It is administered in clinic to the nasal passage as an aerosol through a disposable intranasal atomiser device typically used to administer emergency drugs.Listings from private cosmetic clinics seen by The BMJ hail it as a breakthrough for chronic rhinitis, offering, potentially, several months of relief without discomfort.Haytox was first trademarked in December 2019 by Francesco Barbagallo, a cosmetic physician based in Melbourne, Australia.2 On its website, Barbagallo’s clinic Medico Estetica said the procedure has “absolutely no side effects,”3 although it acknowledged that “the treatment may cause an effect like a minor hay fever attack that can last for up to 10 minutes.” Other clinics, such as Louve Skin Clinic, label the procedure “extremely low risk due to it being non-invasive.”4The Contour Clinic, which has branches in New South…
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