Premature ovarian insufficiency

What you need to knowDiagnosis of premature ovarian insufficiency (POI) is based on menstrual disturbance and raised follicle stimulating hormone in women under 40Untreated POI affects quality of life and increases long term risk of cardiovascular disease, osteoporosis and fracture, and slightly reduces life expectancyWomen with POI should receive hormone therapy and lifestyle advicePOI is associated with infertility, and egg donation may be neededRefer women with a diagnosis of POI to a specialist service to manage their physical, psychological, and reproductive healthPremature ovarian insufficiency (POI) is defined as menopause before the age of 40 (two standard deviations below the average age of menopause).123 It is also known as premature menopause or primary ovarian insufficiency, but POI is the preferred term.1 Premature is preferred to primary to avoid confusion with primary amenorrhoea and to highlight the age of onset. Insufficiency is preferred to failure to reflect possible fluctuation in ovarian function…
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