RSV jab reduced infant hospital admissions by 83%, study reports

The long acting monoclonal antibody nirsevimab (marketed as Beyfortus) reduced respiratory syncytial virus associated hospital admissions in infants by 83%, a study has found.1More than 8000 infants aged 12 months or under in France, Germany, and the UK took part in the study and were randomly assigned to either receive nirsevimab (4037 infants) or standard care (no intervention, 4021 infants) before or during their first RSV season (September and October 2022).The study, funded by the drug companies Sanofi and AstraZeneca, reported that 11 infants (0.3%) in the nirsevimab group and 60 (1.5%) in the standard group were admitted to hospital for RSV associated lower respiratory tract infection. This equated to a nirsevimab efficacy of 83.2% (95% confidence interval 67.8% to 92%; P<0.001).The researchers noted some difference between countries, with the highest efficacy reported in France (89.6%; adjusted 95% confidence interval 58.8% to 98.7%; multiplicity adjusted P<0.001), followed by the UK... Read Original Article: RSV jab reduced infant hospital admissions by 83%, study reports »