NICE lowers cholesterol target for people with cardiovascular disease

Doctors should aim to reduce low density lipoprotein (LDL) cholesterol levels among people with cardiovascular disease to 2.0 mmol/L or less, or non-high density lipoprotein (HDL) cholesterol levels to 2.6 mmol/L or less, the National Institute for Health and Care Excellence (NICE) has advised.1Guidance on reducing the risk of cardiovascular disease (CVD) recommends that if statins alone are not sufficient to reach the blood cholesterol target doctors can consider additional treatments, such as alirocumab, evolocumab, ezetimibe, and inclisiran.An estimated 2.6 million people in England have CVD, and around 2.1 million are treated for elevated cholesterol associated with the condition.NICE estimates that increasing the number of people who reach the LDL target of 2.0 mmol/L or less could reduce CVD events by 50 000-145 000 over 10 years.The 2023-24 updates of the Quality and Outcomes Framework set a similar target to NICE for reducing cholesterol in secondary prevention patients (a non-HDL…
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