Deprivation and learning disabilities linked to increased risk of dying from sepsis, study finds

People from the most socioeconomically deprived groups in England are almost twice as likely to die from sepsis within 30 days of infection than those from the least deprived groups (crude odds ratio 1.80, 95% confidence interval 1.77 to 1.83), according to research.1Researchers from the University of Manchester looked at 224 361 non-covid sepsis cases between 1 January 2019 and 31 June 2022, and compared these to 1 346 166 matched controls. They found that as well as deprivation, comorbidity and learning disabilities were also associated with an increased risk of developing non-covid sepsis and 30 day mortality.Co-author Tjeerd van Staa, health e-research professor at the University of Manchester, said that the findings underscore the “urgent need for sepsis risk prediction models to account for chronic disease status, deprivation status, and learning disabilities, along with infection severity.”Of the sepsis cases assessed, 80% were community acquired and 20% hospital acquired. Only…
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