Vitamin B12

What you need to knowThe clinical picture is the most important factor in assessing the significance of results of blood tests assessing cobalamin (B12) status because there is no “gold standard” test to define deficiencyNeurological symptoms resulting from B12 deficiency may take several months or even years to resolve completelyMeasuring serum biomarkers such as B12 or methylmalonic acid is neither helpful nor indicated in assessing or monitoring clinical improvement, neither is titration of injection frequency based on biomarker assessmentSelf-administration of intramuscular B12 injections can lead to greater patient satisfaction and better health outcomesWhat is vitamin B12?Vitamin B12 (cobalamin) is a water soluble vitamin required for several physiological processes, including normal nervous system functioning, and red blood cell development and maturation. It has antioxidant effects, is a co-factor in mitochondrial energy metabolism, and contributes to DNA synthesis, the methylation cycle, and epigenetic regulation.12 B12 is present in foods of animal origin,…
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