Semaglutide reduces risk of major cardiovascular events by 20%, finds study

A weekly injection of semaglutide (Wegovy) resulted in a 20% reduction in the risk of death from major cardiovascular events in people classed as overweight or obese who were not diabetic, according to trial results published in the New England Journal of Medicine.1The headline results from the Select trial were previously reported by the manufacturer Novo Nordisk in August.Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist and is used to treat type 2 diabetes under its brand name Ozempic. In March, the National Institute for Health and Care Excellence recommended semaglutide can be prescribed to help people lose weight as part of their treatment in a NHS specialist weight management service.23 A planned two year pilot to see if GPs can safely prescribe the drug has yet to start because of supply problems.4The investigators randomly assigned 17 604 patients with pre-existing atheroslerotic cardiovascular disease and a body mass index of…
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