Type 2 diabetes, insulin, and dementia . . . and other stories

Insulin and dementiaObservational studies report that insulin use in people with type 2 diabetes carries an increased risk of dementia. It looks as if that’s because patients who need insulin have more severe disease and worse health rather than because of any direct effect of treatment. A study using administrative healthcare data from British Columbia, Canada, which compared new users of insulin with new users of a non-insulin hypoglycaemic drug found no association between insulin use and all-cause dementia (Diabetes Care doi:10.2337/dc23-0222).Repetitive head impacts and chronic traumatic encephalopathyIt’s the number of head impacts and the associated linear and rotational acceleration rather than the number of concussions that contribute most to brain damage. In a study that used a position exposure matrix to estimate lifetime head injury in 631 players of American football who had donated their brains for research, pathological signs of chronic traumatic encephalopathy were more closely related to…
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