She-Hulk: an incredible case of transfusion associated graft versus host disease
Transfusion associated graft versus host disease (TaGVHD) is a rare complication of blood transfusion in which viable lymphocytes within a blood product engraft (survive and proliferate) in a recipient. This process results in an almost always fatal form of graft versus host disease,1 with donor T cells attacking multiple organs, notably the skin, liver, gastrointestinal tract, and bone marrow.This paper analyses a high profile case of non-lethal TaGVHD due to inadvertent blood contamination of an open wound after a car accident.2 While both donor and recipient survived the crash and contamination, the recipient was left with unexpected side effects, namely inheriting the ability of the donor to transform into an enormous green rage monster.The celebrity nature of this case means that the identities of both donor and recipient as well as the details of the incident are already in the public domain. The donor is Bruce Banner MD, PhD, PhD,…
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