Ann Robinson’s research reviews—27 October 2022

Genital herpes: a sore subjectI was taught that herpes simplex virus type 1 (HSV-1) causes cold sores on the lip while HSV-2 causes genital sores. But that’s all changing, with HSV-1 fast becoming the leading cause of genital herpes in many countries, spread by oral sex or genital to genital contact. And genital herpes concerns us all: according to the World Health Organization, two thirds of the world’s population under 50 years old are infected with HSV-1, and half a billion people aged 15-49 have genital infection due to HSV-1 or HSV-2.Most of what we know about genital herpes comes from studies on HSV-2, and we know much less about HSV-1. This small prospective cohort study of 82 people with their first episode of genital HSV-1 infection found significant levels of genital viral shedding after the initial infection (12.1% of days in a 30 day period at two months and…
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