Tom Nolan’s research reviews—15 September 2022

Cool runningsThe pages of medical journals aren’t the typical place for a Hollywood feel-good film storyline, but I reckon the tale of how a group of people with diabetes collaborated to create the world’s first open-source artificial pancreas and beat the medical device industry at its own game could have the makings of a blockbuster hit. It starts in 2013 when Dana Lewis, founder of the Do-It-Yourself Pancreas System, hacked her continuing glucose monitoring device so that it would wake her at night if her glucose levels became too low or too high. She discovered she wasn’t alone and found hundreds of other people with diabetes and their loved ones who were sharing their DIY solutions and computer code. Nine years later, results from a randomised control trial of the open-source closed-loop automated insulin delivery system (which combines continuous glucose monitoring, calculating insulin requirements, and delivering insulin all in one—the…
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