Insomnia: Large study shows how well different drugs work

Two drugs not yet licensed in the UK, eszopiclone and lemborexant, seem to perform better than others in the acute and long term treatment of insomnia, show the results of a large comparison study.Melatonin, which is licensed in the UK to treat insomnia in adults over the age of 55, did not show overall material benefits, according to the meta-analysis published in the Lancet.1 There was also insufficient evidence to support the prescription of benzodiazepines and zolpidem in the long term treatment of insomnia, found the research, which was funded by the National Institute for Health and Care Research.The study included 154 double blind, randomised controlled trials that involved 44 000 people and 30 licensed or unlicensed drugs and placebo. The researchers compared the effectiveness of different pharmacological treatments for efficacy, acceptability, tolerability and safety in both acute and long term treatment of insomnia disorder.“We looked at all information published…
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