FDA recommends vaccine makers update Covid-19 shots to target Omicron

The Food and Drug Administration is advising vaccine makers to reformulate their Covid-19 shots to target the BA.4 and BA.5 Omicron subvariants as well as the original strain of the virus, the agency announced Thursday, as it seeks to provide people with broader protection against the evolving coronavirus.

The BA.4 and BA.5 variants of Omicron — which have identical forms of the virus’s spike protein that the vaccines are designed to target — together now account for the majority of infections in the United States and have been building in prevalence globally.

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