With little data, doctors struggle to decide which Covid-19 patients should get remdesivir

Now that the federal government has begun distributing the experimental Covid-19 drug remdesivir, hospitals are in a bind. So far, it’s the only medication that has shown benefit for coronavirus patients in rigorous studies. But there isn’t enough for everyone who’s eligible. That leaves doctors with a wrenching ethical decision: Who gets the drug, and who doesn’t?

As if the question wasn’t hard enough on moral grounds alone, it’s made even trickier by a dearth of data: Clinicians still don’t have the fine-grained study results showing which patients are most likely to benefit from the medication. Other antiviral medications work best when given earlier on in the course of illness — and anecdotally, that seems true for remdesivir, too — but it’s hard to make such calls with any certainty if you don’t have robust data.

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