Here are the contenders for STAT Madness 2021. Voting begins Monday

For science, 2020 was a year like no other, as labs around the world shifted their focus to understanding and developing treatments and vaccines against Covid-19. Not surprisingly, research on the novel coronavirus dominates the bracket for this year’s STAT Madness, our annual competition in which readers choose the most important biomedical advance or discovery to emerge from U.S. labs in the past year.

Of the 64 entries selected — from nearly 130 submissions from universities and affiliated research institutions — 15 involve research on Covid. They include characterizing the immune response to the coronavirus; repurposing existing drugs as treatments; understanding why patients’ blood clots; devising tests using CRISPR as well as sewer water; and performing the preclinical work that led to the single-dose Johnson & Johnson vaccine, which is expected to be granted emergency authorization in the U.S. in coming days.

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