3 Immune System Supplements to Prevent the Flu This Winter

3 Immune System Supplements to Prevent the Flu this WinterDo you want to stay flu-free this winter? Are you curious about immune system supplements–wondering if any of the hundreds available are really effective? Many naturopathic and integrative doctors recommend effective, immune system boosters that can be safely taken long-term during the flu season to help lower the likelihood you’ll get the flu.

What About a Flu Shot?

Even conventional doctors agree that prevention is the most effective management strategy for the flu. The most common conventional flu prevention strategy is vaccination. Flu vaccine does not guarantee you will not get the flu, although it may make your symptoms milder if you do. Historically, Medscape reports that the flu vaccine has had 50-60 percent efficacy against infection with influenza A viruses and 70 percent efficacy against influenza B viruses (the two most common types of flu viruses).[1] For the 2012-2013 flu season, they report overall efficacy against influenza A and B virus infections was 56 percent. 

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But that effectiveness rate published by a government agency, the Centers for Disease Control and Prevention (CDC), is strongly disputed by some scientists. In a British Medical Journal editorial published in May, 2013, a Johns Hopkins Medical School scientist blasted the CDC for pushing flu shots saying these federal health authorities vastly overstate the benefits of the flu shot and, for most healthy people, vaccination is unnecessary at best and potentially risky at worst.[2]

Preventing the Flu with Natural Immune System Supplements

Flu vaccine effectiveness and safety continues to be strongly debated among some health experts. But to improve your own odds of escaping the flu in a safe manner, research shows certain natural immune-boosting remedies are safe and effective if taken prophylactically. If you would like use natural medicine to help stay healthy and flu-free this season (either in addition to or in place of the flu vaccine) you’re in luck. Below is a brief discussion of some of the best-researched herbal and nutritional therapies that have been shown to reduce the likelihood of getting the flu or a viral upper respiratory infection during the flu season.

But first, don’t forget the basics: wash your hands frequently; eat a good diet, which means cutting out or vastly reducing sugar and getting plenty of whole, unrefined foods, including whole grains, fruits, vegetables and adequate protein; take a high-quality multivitamin and mineral supplement on an ongoing basis; and live a balanced life that does not include too much stress (this includes getting adequate sleep).

The following immune system boosters are herbal and nutritional supplements that can be used long-term during the flu season to help prevent the flu:

Elderberry: Black elderberries are known to be extremely rich sources of plant compounds called polyphenols, including flavonoids, catechins, and proanthocyanidins, as well as possessing a variety of anti-oxidant properties and enhancing the immune response. In addition, elderberry extracts have shown to help ward off the flu and other respiratory viruses in human clinical trials. For flu prevention, take a spoonful of delicious elderberry syrup (such as Sambucol) twice a day. Higher doses of elderberry syrup have also been found to reduce the severity and duration of the flu.[3]

Echinacea: Perhaps the most recognized herbal supplement today for prevention and treatment of colds and flu, Echinacea has come under much scientific scrutiny to determine its effectiveness and the studies have yielded mixed results, depending, in part, on the type, concentration, and dose of Echinacea extract used. One well-researched Echinacea extract that has proven to help protect individuals against catching colds and flu is a Swiss extract of the fresh roots and aerial parts of organically grown Echinacea purpurea and is called Echinaforce®.[4] Echinaforce® is commonly sold in the U.S. as tablets or liquid. Take as directed on the bottle.

Ginseng: Numerous studies have shown taking either American Ginseng (botanical name: Panaxquinquefolius) or Korean Red Ginseng (also known as Panax ginseng) during the flu season lowers the risk of contracting a cold or the flu.[5] Dosages used in studies have varied depending, in part, on whether the ginseng supplement contained an extract or the whole dried herb and whether it was a liquid, capsule, or tablet. If you’re commonly run-down, stressed, and fatigued, Panax ginseng may be the best option for you as a preventative during the flu season, since this ginseng is also an excellent adaptogen that treats stress-related fatigue. Take as directed on the bottle.

Elderberry, Echinacea, Beta-Glucans, and Red Korean or American Ginseng are just a few of the well-researched immune system boosters that you can safely take throughout the flu season to decrease the chances you’ll get the flu. Beta-glucans, such as those found in the patented supplement Epicor, are another favorite immune system supplement for flu season prevention. Have you tried these or other immune supplements to help you prevent and treat symptoms of the flu? If so, tell your fellow readers in the Comments section below what supplements and herbs have worked best for you. Let’s help each other fight the flu season this year with natural remedies!


[1] Influenza, Medscape, September 16, 2013.

[2] BMJ. 2013 May 16;346:f3037.

[3] International Med Res. 2004;32:132–140.

[4] Wien Med Wochenschr. 2013 Feb;163(3-4):102-5.

[5] J Korean Med Sci. 2012 December; 27(12): 1472–1478.


Originally published in October 2013 and updated.

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